3t6b: Difference between revisions

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{{STRUCTURE_3t6b|  PDB=3t6b  |  SCENE=  }}  
{{STRUCTURE_3t6b|  PDB=3t6b  |  SCENE=  }}  
===Structure of human DPPIII in complex with the opioid peptide Tynorphin, at 2.4 Angstroms===
===Structure of human DPPIII in complex with the opioid peptide Tynorphin, at 2.4 Angstroms===
{{ABSTRACT_PUBMED_022493238}}
{{ABSTRACT_PUBMED_22493238}}
 
==Function==
[[http://www.uniprot.org/uniprot/DPP3_HUMAN DPP3_HUMAN]] Cleaves Arg-Arg-beta-naphthylamide.


==About this Structure==
==About this Structure==
[[3t6b]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T6B OCA].  
[[3t6b]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T6B OCA].  


==See Also==
==Reference==
*[[Dipeptidyl peptidase|Dipeptidyl peptidase]]
<ref group="xtra">PMID:022493238</ref><references group="xtra"/><references/>
[[Category: Dipeptidyl-peptidase III]]
[[Category: Dipeptidyl-peptidase III]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]

Revision as of 18:22, 19 June 2013

Template:STRUCTURE 3t6b

Structure of human DPPIII in complex with the opioid peptide Tynorphin, at 2.4 AngstromsStructure of human DPPIII in complex with the opioid peptide Tynorphin, at 2.4 Angstroms

Template:ABSTRACT PUBMED 22493238

FunctionFunction

[DPP3_HUMAN] Cleaves Arg-Arg-beta-naphthylamide.

About this StructureAbout this Structure

3t6b is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

ReferenceReference

[xtra 1]

  1. Bezerra GA, Dobrovetsky E, Viertlmayr R, Dong A, Binter A, Abramic M, Macheroux P, Dhe-Paganon S, Gruber K. Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6525-30. Epub 2012 Apr 9. PMID:22493238 doi:10.1073/pnas.1118005109

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