1usx: Difference between revisions
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{{STRUCTURE_1usx| PDB=1usx | SCENE= }} | {{STRUCTURE_1usx| PDB=1usx | SCENE= }} | ||
=== | ===Crystal structure of the Newcastle disease virus hemagglutinin-neuraminidase complexed with thiosialoside=== | ||
{{ABSTRACT_PUBMED_15016893}} | {{ABSTRACT_PUBMED_15016893}} | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/HN_NDVB HN_NDVB]] Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion (By similarity). Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins (By similarity). | |||
==About this Structure== | ==About this Structure== | ||
[[1usx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[1usx]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Avian_paramyxovirus_type_1 Avian paramyxovirus type 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1USX OCA]. | ||
==See Also== | ==See Also== | ||
| Line 10: | Line 13: | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:015016893</ref>< | <ref group="xtra">PMID:015016893</ref><references group="xtra"/><references/> | ||
[[Category: Avian paramyxovirus type 1]] | |||
[[Category: Exo-alpha-sialidase]] | [[Category: Exo-alpha-sialidase]] | ||
[[Category: Groves, D.]] | [[Category: Groves, D.]] | ||
[[Category: Itzstein, M | [[Category: Itzstein, M.]] | ||
[[Category: Kiefel, M.]] | [[Category: Kiefel, M.]] | ||
[[Category: Portner, A.]] | [[Category: Portner, A.]] | ||
| Line 21: | Line 24: | ||
[[Category: Zaitsev, V.]] | [[Category: Zaitsev, V.]] | ||
[[Category: Hemagglutinin]] | [[Category: Hemagglutinin]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Neuraminidase]] | [[Category: Neuraminidase]] | ||
[[Category: Sialidase]] | [[Category: Sialidase]] | ||
Revision as of 14:55, 20 November 2013
Crystal structure of the Newcastle disease virus hemagglutinin-neuraminidase complexed with thiosialosideCrystal structure of the Newcastle disease virus hemagglutinin-neuraminidase complexed with thiosialoside
Template:ABSTRACT PUBMED 15016893
FunctionFunction
[HN_NDVB] Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of HN protein to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion (By similarity). Neuraminidase activity ensures the efficient spread of the virus by dissociating the mature virions from the neuraminic acid containing glycoproteins (By similarity).
About this StructureAbout this Structure
1usx is a 3 chain structure with sequence from Avian paramyxovirus type 1. Full crystallographic information is available from OCA.