2bin: Difference between revisions

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[[Image:2bin.gif|left|200px]]<br /><applet load="2bin" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2bin.gif|left|200px]]
caption="2bin, resolution 1.9&Aring;" />
 
'''HUMAN P53 CORE DOMAIN MUTANT M133L-H168R-V203A-N239Y-N268D'''<br />
{{Structure
|PDB= 2bin |SIZE=350|CAPTION= <scene name='initialview01'>2bin</scene>, resolution 1.9&Aring;
|SITE= <scene name='pdbsite=AC1:Zn+Binding+Site+For+Chain+A'>AC1</scene>
|LIGAND= <scene name='pdbligand=ZN:ZINC ION'>ZN</scene>
|ACTIVITY=
|GENE=
}}
 
'''HUMAN P53 CORE DOMAIN MUTANT M133L-H168R-V203A-N239Y-N268D'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2BIN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=AC1:Zn+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIN OCA].  
2BIN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BIN OCA].  


==Reference==
==Reference==
Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations., Joerger AC, Ang HC, Veprintsev DB, Blair CM, Fersht AR, J Biol Chem. 2005 Apr 22;280(16):16030-7. Epub 2005 Feb 9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15703170 15703170]
Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations., Joerger AC, Ang HC, Veprintsev DB, Blair CM, Fersht AR, J Biol Chem. 2005 Apr 22;280(16):16030-7. Epub 2005 Feb 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15703170 15703170]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: tumor suppressor]]
[[Category: tumor suppressor]]


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