4e86: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_4e86| PDB=4e86 | SCENE= }} | {{STRUCTURE_4e86| PDB=4e86 | SCENE= }} | ||
===Crystal structure of human alpha-defensin 5, HD5 (Leu29Aba mutant)=== | ===Crystal structure of human alpha-defensin 5, HD5 (Leu29Aba mutant)=== | ||
{{ | {{ABSTRACT_PUBMED_22573326}} | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/DEF5_HUMAN DEF5_HUMAN]] Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing.<ref>PMID:12021776</ref> <ref>PMID:15616305</ref> <ref>PMID:17088326</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[4e86]] is a 9 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E86 OCA]. | [[4e86]] is a 9 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E86 OCA]. | ||
== | ==Reference== | ||
<ref group="xtra">PMID:022573326</ref><references group="xtra"/><references/> | |||
[[Category: Pazgier, M.]] | [[Category: Pazgier, M.]] | ||
[[Category: Wu, X.]] | [[Category: Wu, X.]] | ||