2b6a: Difference between revisions

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OCA

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-[[Image:2b6a.jpg|left|200px]]<br /><applet load="2b6a" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2b6a.jpg|left|200px]]
-caption="2b6a, resolution 2.650&Aring;" />
-'''Crystal structure of HIV-1 reverse transcriptase (RT) in complex with THR-50'''<br />
+ {{Structure
+|PDB= 2b6a |SIZE=350|CAPTION= <scene name='initialview01'>2b6a</scene>, resolution 2.650&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=T50:1-(2,6-DIFLUOROBENZYL)-2-(2,6-DIFLUOROPHENYL)-4-METHYL-1H-BENZIMIDAZOLE'>T50</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49]
+|GENE= POL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])
+}}
+'''Crystal structure of HIV-1 reverse transcriptase (RT) in complex with THR-50'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-B6A is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=T50:'>T50</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6A OCA].
+B6A is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6A OCA].
 ==Reference==
-Synthesis and biological activity of novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 2-Aryl-substituted benzimidazoles., Roth T, Morningstar ML, Boyer PL, Hughes SH, Buckheit RW Jr, Michejda CJ, J Med Chem. 1997 Dec 19;40(26):4199-207. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9435891 9435891]
+Synthesis and biological activity of novel nonnucleoside inhibitors of HIV-1 reverse transcriptase. 2-Aryl-substituted benzimidazoles., Roth T, Morningstar ML, Boyer PL, Hughes SH, Buckheit RW Jr, Michejda CJ, J Med Chem. 1997 Dec 19;40(26):4199-207. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9435891 9435891]
 [[Category: Human immunodeficiency virus 1]]
 [[Category: Protein complex]]
@@ Line 25: / Line 34: @@
 [[Category: Zhang, W.]]
 [[Category: T50]]
-[[Category: aids]]
+[[Category: aid]]
 [[Category: drug design]]
 [[Category: hiv]]
@@ Line 32: / Line 41: @@
 [[Category: rt]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:34:37 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:58:08 2008''