Adenylate kinase: Difference between revisions

← Older edit Newer edit →

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel

@@ Line 1: / Line 1: @@
+<StructureSection load="" size="450" color="" frame="true"  spin="on" Scene ="Journal:JBIC:1/Jbic1_opening/2" align="right" caption="[[3l0p]] Crystal structure of cobalt bound adenylate kinase from ''Desulfovibrio gigas''">
 [[Image:3l0p.jpg|left|200px|thumb|Crystal Structure of Adenylate kinase [[3l0p]]]]
-{{STRUCTURE_3l0p|  PDB=3l0p  | SIZE=400| SCENE= |right|CAPTION=Adenylate kinase complex with iron and glycerol [[3l0p]] }}
 [[Adenylate kinase]] (ADK, EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.3 2.7.4.3]) is a phosphotransferase which catalyzes the interconversion of ADP to ATP+AMP.  ADK is important in cellular energy homeostasis. Dinucleotides polyphosphates like diadenosine pentaphosphate
 (AP5) inhibit ADK. The images at the left and at the right correspond to one representative ADK, ''i.e.'' the crystal structure of Adenylate kinase from ''Desulfovibrio gigas'' ([[3l0p]]).
 __NOTOC__
-<StructureSection load="" size="600" color="" frame="true"  spin="on" Scene ="Journal:JBIC:1/Jbic1_opening/2" align="right" caption="[[3l0p]] Crystal structure of cobalt bound adenylate kinase from ''Desulfovibrio gigas''">
 &nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Adenylate kinase is an essential catalyst for cellular growth and multiplication. ADK belongs to a family of enzymes essential to life, and is highly abundant inside the cell. It is involved in the reversible transfer of the terminal phosphate group from Mg2+ATP to Mg2+AMP with high energy turnover: Mg2+ATP + AMP&#8596;Mg2+ADP + ADP.
 <br />