2b1v: Difference between revisions
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
[[Image:2b1v.gif|left|200px]] | [[Image:2b1v.gif|left|200px]] | ||
'''Human estrogen receptor alpha ligand-binding domain in complex with OBCP-1M and a glucocorticoid receptor interacting protein 1 NR box II peptide''' | {{Structure | ||
|PDB= 2b1v |SIZE=350|CAPTION= <scene name='initialview01'>2b1v</scene>, resolution 1.80Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=458:4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL'>458</scene> | |||
|ACTIVITY= | |||
|GENE= ESR1, ESR, NR3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Human estrogen receptor alpha ligand-binding domain in complex with OBCP-1M and a glucocorticoid receptor interacting protein 1 NR box II peptide''' | |||
==Overview== | ==Overview== | ||
Line 10: | Line 19: | ||
==About this Structure== | ==About this Structure== | ||
2B1V is a [ | 2B1V is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B1V OCA]. | ||
==Reference== | ==Reference== | ||
Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity., Hsieh RW, Rajan SS, Sharma SK, Guo Y, DeSombre ER, Mrksich M, Greene GL, J Biol Chem. 2006 Jun 30;281(26):17909-19. Epub 2006 Apr 28. PMID:[http:// | Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity., Hsieh RW, Rajan SS, Sharma SK, Guo Y, DeSombre ER, Mrksich M, Greene GL, J Biol Chem. 2006 Jun 30;281(26):17909-19. Epub 2006 Apr 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16648639 16648639] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
Line 25: | Line 34: | ||
[[Category: lbd]] | [[Category: lbd]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:56:33 2008'' |