4j2a: Difference between revisions
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{{STRUCTURE_4j2a| PDB=4j2a | SCENE= }} | |||
===RB69 DNA Polymerase L415A Ternary Complex=== | |||
{{ABSTRACT_PUBMED_23921641}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DPOL_BPR69 DPOL_BPR69]] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction. | |||
==About this Structure== | |||
[[4j2a]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J2A OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023921641</ref><references group="xtra"/><references/> | |||
[[Category: DNA-directed DNA polymerase]] | |||
[[Category: Konigsberg, W H.]] | |||
[[Category: Wang, J.]] | |||
[[Category: Xia, S.]] | |||
[[Category: Dna polymerase]] | |||
[[Category: L415a]] | |||
[[Category: Polymerase]] | |||
[[Category: Rb69]] | |||
[[Category: Transferase-dna complex]] | |||
Revision as of 20:37, 19 February 2014
RB69 DNA Polymerase L415A Ternary ComplexRB69 DNA Polymerase L415A Ternary Complex
Template:ABSTRACT PUBMED 23921641
FunctionFunction
[DPOL_BPR69] This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction.
About this StructureAbout this Structure
4j2a is a 3 chain structure. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Xia S, Wood M, Bradley MJ, De La Cruz EM, Konigsberg WH. Alteration in the cavity size adjacent to the active site of RB69 DNA polymerase changes its conformational dynamics. Nucleic Acids Res. 2013 Oct;41(19):9077-89. doi: 10.1093/nar/gkt674. Epub 2013, Aug 5. PMID:23921641 doi:http://dx.doi.org/10.1093/nar/gkt674