4hq0: Difference between revisions
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{{STRUCTURE_4hq0| PDB=4hq0 | SCENE= }} | |||
===Crystal Structure of mutant form of Caspase-7=== | |||
{{ABSTRACT_PUBMED_23897474}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CASP7_HUMAN CASP7_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death. | |||
==About this Structure== | |||
[[4hq0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HQ0 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023897474</ref><references group="xtra"/><references/> | |||
[[Category: Caspase-7]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Bae, K H.]] | |||
[[Category: Chung, S J.]] | |||
[[Category: Kang, H J.]] | |||
[[Category: Kim, S J.]] | |||
[[Category: Lee, Y.]] | |||
[[Category: Hydrolase]] |