4hq0: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4hq0|  PDB=4hq0  |  SCENE=  }}
===Crystal Structure of mutant form of Caspase-7===
{{ABSTRACT_PUBMED_23897474}}


The entry 4hq0 is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/CASP7_HUMAN CASP7_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.


Authors: Lee, Y., Kang, H.J., Bae, K.-H., Kim, S.J., Chung, S.J.
==About this Structure==
[[4hq0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HQ0 OCA].  


Description: Crystal Structure of mutant form of Caspase-7
==Reference==
<ref group="xtra">PMID:023897474</ref><references group="xtra"/><references/>
[[Category: Caspase-7]]
[[Category: Homo sapiens]]
[[Category: Bae, K H.]]
[[Category: Chung, S J.]]
[[Category: Kang, H J.]]
[[Category: Kim, S J.]]
[[Category: Lee, Y.]]
[[Category: Hydrolase]]

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