2ath: Difference between revisions

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[[Image:2ath.gif|left|200px]]<br /><applet load="2ath" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ath.gif|left|200px]]
caption="2ath, resolution 2.28&Aring;" />
 
'''Crystal structure of the ligand binding domain of human PPAR-gamma im complex with an agonist'''<br />
{{Structure
|PDB= 2ath |SIZE=350|CAPTION= <scene name='initialview01'>2ath</scene>, resolution 2.28&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=3EA:2-{5-[3-(7-PROPYL-3-TRIFLUOROMETHYLBENZO[D]ISOXAZOL-6-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID'>3EA</scene>
|ACTIVITY=
|GENE=
}}
 
'''Crystal structure of the ligand binding domain of human PPAR-gamma im complex with an agonist'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2ATH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=3EA:'>3EA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ATH OCA].  
2ATH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ATH OCA].  


==Reference==
==Reference==
Novel indole-based peroxisome proliferator-activated receptor agonists: design, SAR, structural biology, and biological activities., Mahindroo N, Huang CF, Peng YH, Wang CC, Liao CC, Lien TW, Chittimalla SK, Huang WJ, Chai CH, Prakash E, Chen CP, Hsu TA, Peng CH, Lu IL, Lee LH, Chang YW, Chen WC, Chou YC, Chen CT, Goparaju CM, Chen YS, Lan SJ, Yu MC, Chen X, Chao YS, Wu SY, Hsieh HP, J Med Chem. 2005 Dec 29;48(26):8194-208. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16366601 16366601]
Novel indole-based peroxisome proliferator-activated receptor agonists: design, SAR, structural biology, and biological activities., Mahindroo N, Huang CF, Peng YH, Wang CC, Liao CC, Lien TW, Chittimalla SK, Huang WJ, Chai CH, Prakash E, Chen CP, Hsu TA, Peng CH, Lu IL, Lee LH, Chang YW, Chen WC, Chou YC, Chen CT, Goparaju CM, Chen YS, Lan SJ, Yu MC, Chen X, Chao YS, Wu SY, Hsieh HP, J Med Chem. 2005 Dec 29;48(26):8194-208. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16366601 16366601]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: ppar]]
[[Category: ppar]]


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