2anj: Difference between revisions

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[[Image:2anj.jpg|left|200px]]<br /><applet load="2anj" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2anj.jpg|left|200px]]
caption="2anj, resolution 2.10&Aring;" />
 
'''Crystal Structure of the Glur2 Ligand Binding Core (S1S2J-Y450W) Mutant in Complex With the Partial Agonist Kainic Acid at 2.1 A Resolution'''<br />
{{Structure
|PDB= 2anj |SIZE=350|CAPTION= <scene name='initialview01'>2anj</scene>, resolution 2.10&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=KAI:3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE'>KAI</scene>
|ACTIVITY=
|GENE= Gria2, Glur2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])
}}
 
'''Crystal Structure of the Glur2 Ligand Binding Core (S1S2J-Y450W) Mutant in Complex With the Partial Agonist Kainic Acid at 2.1 A Resolution'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2ANJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=KAI:'>KAI</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ANJ OCA].  
2ANJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ANJ OCA].  


==Reference==
==Reference==
A binding site tyrosine shapes desensitization kinetics and agonist potency at GluR2. A mutagenic, kinetic, and crystallographic study., Holm MM, Naur P, Vestergaard B, Geballe MT, Gajhede M, Kastrup JS, Traynelis SF, Egebjerg J, J Biol Chem. 2005 Oct 21;280(42):35469-76. Epub 2005 Aug 15. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16103115 16103115]
A binding site tyrosine shapes desensitization kinetics and agonist potency at GluR2. A mutagenic, kinetic, and crystallographic study., Holm MM, Naur P, Vestergaard B, Geballe MT, Gajhede M, Kastrup JS, Traynelis SF, Egebjerg J, J Biol Chem. 2005 Oct 21;280(42):35469-76. Epub 2005 Aug 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16103115 16103115]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: mutant]]
[[Category: mutant]]


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