2a9z: Difference between revisions

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[[Image:2a9z.gif|left|200px]]<br /><applet load="2a9z" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2a9z.gif|left|200px]]
caption="2a9z, resolution 1.35&Aring;" />
 
'''Crystal structure of T. gondii adenosine kinase complexed with N6-dimethyladenosine and AMP-PCP'''<br />
{{Structure
|PDB= 2a9z |SIZE=350|CAPTION= <scene name='initialview01'>2a9z</scene>, resolution 1.35&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=26A:6N-DIMETHYLADENOSINE'>26A</scene> and <scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER'>ACP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20]
|GENE= AK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5811 Toxoplasma gondii])
}}
 
'''Crystal structure of T. gondii adenosine kinase complexed with N6-dimethyladenosine and AMP-PCP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2A9Z is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii] with <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=26A:'>26A</scene> and <scene name='pdbligand=ACP:'>ACP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Adenosine_kinase Adenosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.20 2.7.1.20] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A9Z OCA].  
2A9Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A9Z OCA].  


==Reference==
==Reference==
Substrate analogs induce an intermediate conformational change in Toxoplasma gondii adenosine kinase., Zhang Y, El Kouni MH, Ealick SE, Acta Crystallogr D Biol Crystallogr. 2007 Feb;63(Pt 2):126-34. Epub 2007, Jan 16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17242506 17242506]
Substrate analogs induce an intermediate conformational change in Toxoplasma gondii adenosine kinase., Zhang Y, El Kouni MH, Ealick SE, Acta Crystallogr D Biol Crystallogr. 2007 Feb;63(Pt 2):126-34. Epub 2007, Jan 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17242506 17242506]
[[Category: Adenosine kinase]]
[[Category: Adenosine kinase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: ribokinase fold; alpha/beta; intermediate conformation]]
[[Category: ribokinase fold; alpha/beta; intermediate conformation]]


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