2a4z: Difference between revisions

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OCA

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-[[Image:2a4z.gif|left|200px]]<br /><applet load="2a4z" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2a4z.gif|left|200px]]
-caption="2a4z, resolution 2.900&Aring;" />
-'''Crystal Structure of human PI3Kgamma complexed with AS604850'''<br />
+ {{Structure
+|PDB= 2a4z |SIZE=350|CAPTION= <scene name='initialview01'>2a4z</scene>, resolution 2.900&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=BYM:(5E)-5-[(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)METHYLENE]-1,3-THIAZOLIDINE-2,4-DIONE'>BYM</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Phosphatidylinositol-4,5-bisphosphate_3-kinase Phosphatidylinositol-4,5-bisphosphate 3-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.153 2.7.1.153]
+|GENE=
+}}
+'''Crystal Structure of human PI3Kgamma complexed with AS604850'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-A4Z is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=BYM:'>BYM</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Phosphatidylinositol-4,5-bisphosphate_3-kinase Phosphatidylinositol-4,5-bisphosphate 3-kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.153 2.7.1.153] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A4Z OCA].
+A4Z is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A4Z OCA].
 ==Reference==
-Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis., Camps M, Ruckle T, Ji H, Ardissone V, Rintelen F, Shaw J, Ferrandi C, Chabert C, Gillieron C, Francon B, Martin T, Gretener D, Perrin D, Leroy D, Vitte PA, Hirsch E, Wymann MP, Cirillo R, Schwarz MK, Rommel C, Nat Med. 2005 Sep;11(9):936-43. Epub 2005 Aug 28. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16127437 16127437]
+Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis., Camps M, Ruckle T, Ji H, Ardissone V, Rintelen F, Shaw J, Ferrandi C, Chabert C, Gillieron C, Francon B, Martin T, Gretener D, Perrin D, Leroy D, Vitte PA, Hirsch E, Wymann MP, Cirillo R, Schwarz MK, Rommel C, Nat Med. 2005 Sep;11(9):936-43. Epub 2005 Aug 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16127437 16127437]
 [[Category: Homo sapiens]]
 [[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
@@ Line 38: / Line 47: @@
 [[Category: protein-inhibitor complex]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:23:38 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:45:27 2008''