4ivb: Difference between revisions
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{{STRUCTURE_4ivb| PDB=4ivb | SCENE= }} | |||
===JAK1 kinase (JH1 domain) in complex with the inhibitor TRANS-4-{2-[(1R)-1-HYDROXYETHYL]IMIDAZO[4,5-D]PYRROLO[2,3-B]PYRIDIN-1(6H)-YL}CYCLOHEXANECARBONITRILE=== | |||
{{ABSTRACT_PUBMED_23659214}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/JAK1_HUMAN JAK1_HUMAN]] Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor. | |||
==About this Structure== | |||
[[4ivb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IVB OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023659214</ref><references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Non-specific protein-tyrosine kinase]] | |||
[[Category: Eigenbrot, C.]] | |||
[[Category: Steffek, M.]] | |||
[[Category: Phosphotransfer]] | |||
[[Category: Protein kinase]] | |||
[[Category: Transferase-transferase inhibitor complex]] |