4hra: Difference between revisions
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{{STRUCTURE_4hra| PDB=4hra | SCENE= }} | |||
===Crystal Structure of DOT1L in Complex with EPZ-5676=== | |||
{{ABSTRACT_PUBMED_23801631}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DOT1L_HUMAN DOT1L_HUMAN]] Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA. | |||
==About this Structure== | |||
[[4hra]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HRA OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023801631</ref><references group="xtra"/><references/> | |||
[[Category: Histone-lysine N-methyltransferase]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Jin, L.]] | |||
[[Category: Histone lysine methyltransferase]] | |||
[[Category: Transferase]] | |||
[[Category: Transferase-transferase inhibitor complex]] |