4hra: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4hra|  PDB=4hra  |  SCENE=  }}
===Crystal Structure of DOT1L in Complex with EPZ-5676===
{{ABSTRACT_PUBMED_23801631}}


The entry 4hra is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/DOT1L_HUMAN DOT1L_HUMAN]] Histone methyltransferase. Methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones. Binds to DNA.


Authors: Jin, L.
==About this Structure==
[[4hra]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HRA OCA].  


Description: Crystal Structure of DOT1L in Complex with EPZ-5676
==Reference==
<ref group="xtra">PMID:023801631</ref><references group="xtra"/><references/>
[[Category: Histone-lysine N-methyltransferase]]
[[Category: Homo sapiens]]
[[Category: Jin, L.]]
[[Category: Histone lysine methyltransferase]]
[[Category: Transferase]]
[[Category: Transferase-transferase inhibitor complex]]

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