1zuc: Difference between revisions

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[[Image:1zuc.gif|left|200px]]<br /><applet load="1zuc" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1zuc.gif|left|200px]]
caption="1zuc, resolution 2.00&Aring;" />
 
'''Progesterone receptor ligand binding domain in complex with the nonsteroidal agonist tanaproget'''<br />
{{Structure
|PDB= 1zuc |SIZE=350|CAPTION= <scene name='initialview01'>1zuc</scene>, resolution 2.00&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=T98:5-(4,4-DIMETHYL-2-THIOXO-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-6-YL)-1-METHYL-1H-PYRROLE-2-CARBONITRILE'>T98</scene>
|ACTIVITY=
|GENE= PGR, NR3C3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Progesterone receptor ligand binding domain in complex with the nonsteroidal agonist tanaproget'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1ZUC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=T98:'>T98</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZUC OCA].  
1ZUC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZUC OCA].  


==Reference==
==Reference==
Molecular and pharmacological properties of a potent and selective novel nonsteroidal progesterone receptor agonist tanaproget., Zhang Z, Olland AM, Zhu Y, Cohen J, Berrodin T, Chippari S, Appavu C, Li S, Wilhem J, Chopra R, Fensome A, Zhang P, Wrobel J, Unwalla RJ, Lyttle CR, Winneker RC, J Biol Chem. 2005 Aug 5;280(31):28468-75. Epub 2005 Jun 3. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15937332 15937332]
Molecular and pharmacological properties of a potent and selective novel nonsteroidal progesterone receptor agonist tanaproget., Zhang Z, Olland AM, Zhu Y, Cohen J, Berrodin T, Chippari S, Appavu C, Li S, Wilhem J, Chopra R, Fensome A, Zhang P, Wrobel J, Unwalla RJ, Lyttle CR, Winneker RC, J Biol Chem. 2005 Aug 5;280(31):28468-75. Epub 2005 Jun 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15937332 15937332]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: tanaproget]]
[[Category: tanaproget]]


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