Peroxiredoxin: Difference between revisions

From Proteopedia
Jump to navigation Jump to search
Michal Harel (talk | contribs)
No edit summary
Michal Harel (talk | contribs)
No edit summary
Line 42: Line 42:
[[2i81]] - 2Cys-Prx – ''Plasmodium vivax''<br />
[[2i81]] - 2Cys-Prx – ''Plasmodium vivax''<br />
[[1qmv]] - h2Cys-Prx – human<br />
[[1qmv]] - h2Cys-Prx – human<br />
[[2a4v]] – yPrx dot5 C-termianl (mutant) – yeast<br />
[[3cmi]] – yPrx hyr1<br />
[[4g2e]] – Prx – ''Sulfolobus tokodaii''<br />
[[3sbc]] – yPrx Tsa1 (mutant)<br />
[[1uul]] - 2Cys-Prx – ''Trypanosoma cruzi''<br />
[[1we0]] – Prx – ''Amphibacillus xylanus''<br />
[[2cv4]], [[2cx3]], [[2cx4]] – Prx – ''Aeropyrum pernix''<br />
[[3drn]] – SsPrx – ''Sulfolobus solfataricus''<br />
[[3hjp]] – SsPrx (mutant)<br />
[[3ixr]] – Prx PRXQ (mutant) – ''Xylella fastidiosa''<br />
===Peroxiredoxin 1===
[[2rii]], [[3hy2]] – hPrx 1 (mutant)+sulfiredoxin 1<br />
[[2rii]], [[3hy2]] – hPrx 1 (mutant)+sulfiredoxin 1<br />
[[2z9s]] – Prx 1 (mutant) - rat<br />
[[2z9s]] – Prx 1 (mutant) - rat<br />
===Peroxiredoxin 2===
[[1tp9]] – Prx  II – ''Populus trichocarpa''<br />
[[2pwj]] – Prx II – garden pea<br />
[[4dsq]], [[4dsr]], [[4h86]] – yPrx II<br />
[[4dss]] – yPrx II (mutant) + thioredoxin II<br />
===Peroxiredoxin 3===
[[1zye]] – Prx III (mutant) – bovine<br />
===Peroxiredoxin 4===
[[3tjf]], [[3tjg]], [[3tjj]], [[3tjk]], [[3tkr]] - hPrx 4 (mutant)<br />
[[3tjf]], [[3tjg]], [[3tjj]], [[3tjk]], [[3tkr]] - hPrx 4 (mutant)<br />
[[3qpm]] – Prx 4 – ''Larimichtys crocea''<br />
[[3qpm]] – Prx 4 – ''Larimichtys crocea''<br />
[[2pn8]], [[3tjb]], [[3tkp]], [[3tkq]], [[3tks]]  – hPrx 4<br />
[[2pn8]], [[3tjb]], [[3tkp]], [[3tkq]], [[3tks]]  – hPrx 4<br />
===Peroxiredoxin 5===
[[1urm]] – hPrx 5 (mutant) – human<br />
[[1urm]] – hPrx 5 (mutant) – human<br />
[[2vl2]], [[2vl3]], [[2vl9]], [[1h4o]], [[1hd2]], [[1oc3]]  – hPrx 5<br />
[[2vl2]], [[2vl3]], [[2vl9]], [[1h4o]], [[1hd2]], [[1oc3]]  – hPrx 5<br />
Line 52: Line 82:
[[2wfc]] – lPrx 5 - lugworm<br />
[[2wfc]] – lPrx 5 - lugworm<br />
[[2xhf]] – Prx 5 – ''Alvinella pompejana''<br />
[[2xhf]] – Prx 5 – ''Alvinella pompejana''<br />
===Peroxiredoxin 6===
[[2v2g]] – lPrx 6 <br />
[[2v2g]] – lPrx 6 <br />
[[2v32]], [[2v41]] – lPrx 6 (mutant)<br />
[[2v32]], [[2v41]] – lPrx 6 (mutant)<br />
[[2a4v]] – yPrx dot5 C-termianl (mutant) – yeast<br />
[[3cmi]] – yPrx hyr1<br />
[[1tp9]] – Prx  II – ''Populus trichocarpa''<br />
[[2pwj]] – Prx II – garden pea<br />
[[4g2e]] – Prx – ''Sulfolobus tokodaii''<br />
[[4dsq]], [[4dsr]], [[4h86]] – yPrx II<br />
[[3sbc]] – yPrx Tsa1 (mutant)<br />
[[4dss]] – yPrx II (mutant) + thioredoxin II<br />
[[1uul]] - 2Cys-Prx – ''Trypanosoma cruzi''<br />
[[1we0]] – Prx – ''Amphibacillus xylanus''<br />
[[1zye]] – Prx III (mutant) – bovine<br />
[[2cv4]], [[2cx3]], [[2cx4]] – Prx – ''Aeropyrum pernix''<br />
[[3drn]] – SsPrx – ''Sulfolobus solfataricus''<br />
[[3hjp]] – SsPrx (mutant)<br />
[[3ixr]] – Prx PRXQ (mutant) – ''Xylella fastidiosa''<br />




[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 15:24, 14 May 2013

File:1qq2.png
Crystal Structure of Peroxiredoxin (1qq2)

Template:STRUCTURE 1qq2











Peroxiredoxin (Prx) is an antioxidant enzyme. In the Prxs the active-site Cys is oxidized to sulfenic acid byperoxide. The Prxs are divided into typical 2-Cys Prx, atypical 2-Cys Prx and 1-Cys Prx. Prx 5 is expressed in mammalian tissue. The images at the left and at the right correspond to one representative Prx, i.e. the crystal structure of Peroxiredoxin from rat (1qq2).








3D Structures of Peroxiredoxin3D Structures of Peroxiredoxin

Updated February 2013

1qq2 – 2Cys-Prx – rat
2c0d – Pf2Cys-Prx – Plasmodium falciparum
1xiy – Pf1Cys-Prx
1xcc, 2h01, 3tb2 - 1Cys-Prx – Plasmodium yoelii
2i81 - 2Cys-Prx – Plasmodium vivax
1qmv - h2Cys-Prx – human
2a4v – yPrx dot5 C-termianl (mutant) – yeast
3cmi – yPrx hyr1
4g2e – Prx – Sulfolobus tokodaii
3sbc – yPrx Tsa1 (mutant)
1uul - 2Cys-Prx – Trypanosoma cruzi
1we0 – Prx – Amphibacillus xylanus
2cv4, 2cx3, 2cx4 – Prx – Aeropyrum pernix
3drn – SsPrx – Sulfolobus solfataricus
3hjp – SsPrx (mutant)
3ixr – Prx PRXQ (mutant) – Xylella fastidiosa

Peroxiredoxin 1Peroxiredoxin 1

2rii, 3hy2 – hPrx 1 (mutant)+sulfiredoxin 1
2z9s – Prx 1 (mutant) - rat

Peroxiredoxin 2Peroxiredoxin 2

1tp9 – Prx II – Populus trichocarpa
2pwj – Prx II – garden pea
4dsq, 4dsr, 4h86 – yPrx II
4dss – yPrx II (mutant) + thioredoxin II

Peroxiredoxin 3Peroxiredoxin 3

1zye – Prx III (mutant) – bovine

Peroxiredoxin 4Peroxiredoxin 4

3tjf, 3tjg, 3tjj, 3tjk, 3tkr - hPrx 4 (mutant)
3qpm – Prx 4 – Larimichtys crocea
2pn8, 3tjb, 3tkp, 3tkq, 3tks – hPrx 4

Peroxiredoxin 5Peroxiredoxin 5

1urm – hPrx 5 (mutant) – human
2vl2, 2vl3, 2vl9, 1h4o, 1hd2, 1oc3 – hPrx 5
3mng – hPrx 5+DTT
2wfc – lPrx 5 - lugworm
2xhf – Prx 5 – Alvinella pompejana

Peroxiredoxin 6Peroxiredoxin 6

2v2g – lPrx 6
2v32, 2v41 – lPrx 6 (mutant)

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel, Joel L. Sussman