1zsf: Difference between revisions
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[[Image:1zsf.gif|left|200px]] | [[Image:1zsf.gif|left|200px]] | ||
'''Crystal Structure of Complex of a Hydroxyethylamine Inhibitor with HIV-1 Protease at 2.0A Resolution''' | {{Structure | ||
|PDB= 1zsf |SIZE=350|CAPTION= <scene name='initialview01'>1zsf</scene>, resolution 1.98Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=NH2:AMINO GROUP'>NH2</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] | |||
|GENE= | |||
}} | |||
'''Crystal Structure of Complex of a Hydroxyethylamine Inhibitor with HIV-1 Protease at 2.0A Resolution''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1ZSF is a [ | 1ZSF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZSF OCA]. | ||
==Reference== | ==Reference== | ||
On the role of the R configuration of the reaction-intermediate isostere in HIV-1 protease-inhibitor binding: X-ray structure at 2.0 A resolution., Duskova J, Dohnalek J, Skalova T, Petrokova H, Vondrackova E, Hradilek M, Konvalinka J, Soucek M, Brynda J, Fabry M, Sedlacek J, Hasek J, Acta Crystallogr D Biol Crystallogr. 2006 May;62(Pt 5):489-97. Epub 2006, Apr 19. PMID:[http:// | On the role of the R configuration of the reaction-intermediate isostere in HIV-1 protease-inhibitor binding: X-ray structure at 2.0 A resolution., Duskova J, Dohnalek J, Skalova T, Petrokova H, Vondrackova E, Hradilek M, Konvalinka J, Soucek M, Brynda J, Fabry M, Sedlacek J, Hasek J, Acta Crystallogr D Biol Crystallogr. 2006 May;62(Pt 5):489-97. Epub 2006, Apr 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16627941 16627941] | ||
[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
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[[Category: hiv; protease; inhibitor; peptidomimetic]] | [[Category: hiv; protease; inhibitor; peptidomimetic]] | ||
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