4ir4: Difference between revisions
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==Crystal Structure of the bromodomain of human BAZ2B in complex with 1-[7-(morpholin-4-yl)-1-(pyridin-2-yl)indolizin-3-yl]ethanone (GSK2834113A)== | |||
<StructureSection load='4ir4' size='340' side='right' caption='[[4ir4]], [[Resolution|resolution]] 2.05Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4ir4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IR4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IR4 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IR4:1-[7-(MORPHOLIN-4-YL)-1-(PYRIDIN-2-YL)INDOLIZIN-3-YL]ETHANONE'>IR4</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ir3|4ir3]], [[4ir5|4ir5]], [[4ir6|4ir6]]</td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAZ2B, KIAA1476 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ir4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ir4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ir4 RCSB], [http://www.ebi.ac.uk/pdbsum/4ir4 PDBsum]</span></td></tr> | ||
[[4ir4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IR4 OCA]. | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN]] May play a role in transcriptional regulation interacting with ISWI. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith, C H | [[Category: Arrowsmith, C H]] | ||
[[Category: Bountra, C | [[Category: Bountra, C]] | ||
[[Category: Chaikuad, A | [[Category: Chaikuad, A]] | ||
[[Category: Chen, P | [[Category: Chen, P]] | ||
[[Category: Chung, C W | [[Category: Chung, C W]] | ||
[[Category: Delft, F von | [[Category: Delft, F von]] | ||
[[Category: Drewry, D | [[Category: Drewry, D]] | ||
[[Category: Edwards, A M | [[Category: Edwards, A M]] | ||
[[Category: Fedorov, O | [[Category: Fedorov, O]] | ||
[[Category: Felletar, I | [[Category: Felletar, I]] | ||
[[Category: Filippakopoulos, P | [[Category: Filippakopoulos, P]] | ||
[[Category: Knapp, S | [[Category: Knapp, S]] | ||
[[Category: Krojer, T | [[Category: Krojer, T]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Acetylated lysine binding protein]] | [[Category: Acetylated lysine binding protein]] | ||
[[Category: Bromodomain]] | [[Category: Bromodomain]] | ||
[[Category: Kiaa1476]] | [[Category: Kiaa1476]] | ||
[[Category: Sgc]] | [[Category: Sgc]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Walp4]] | [[Category: Walp4]] | ||
Revision as of 22:12, 25 December 2014
Crystal Structure of the bromodomain of human BAZ2B in complex with 1-[7-(morpholin-4-yl)-1-(pyridin-2-yl)indolizin-3-yl]ethanone (GSK2834113A)Crystal Structure of the bromodomain of human BAZ2B in complex with 1-[7-(morpholin-4-yl)-1-(pyridin-2-yl)indolizin-3-yl]ethanone (GSK2834113A)
Structural highlights
Function[BAZ2B_HUMAN] May play a role in transcriptional regulation interacting with ISWI. |
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