3ebp: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_3ebp| PDB=3ebp | SCENE= }} | {{STRUCTURE_3ebp| PDB=3ebp | SCENE= }} | ||
===Glycogen Phosphorylase b/flavopiridol complex=== | ===Glycogen Phosphorylase b/flavopiridol complex=== | ||
{{ABSTRACT_PUBMED_23279842}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PYGM_RABIT PYGM_RABIT]] Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. | |||
==About this Structure== | ==About this Structure== | ||
| Line 12: | Line 11: | ||
==See Also== | ==See Also== | ||
*[[Glycogen Phosphorylase|Glycogen Phosphorylase]] | *[[Glycogen Phosphorylase|Glycogen Phosphorylase]] | ||
==Reference== | |||
<ref group="xtra">PMID:023279842</ref><references group="xtra"/><references/> | |||
[[Category: Oryctolagus cuniculus]] | [[Category: Oryctolagus cuniculus]] | ||
[[Category: Phosphorylase]] | [[Category: Phosphorylase]] | ||
Revision as of 15:37, 11 December 2013
Glycogen Phosphorylase b/flavopiridol complexGlycogen Phosphorylase b/flavopiridol complex
Template:ABSTRACT PUBMED 23279842
FunctionFunction
[PYGM_RABIT] Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
About this StructureAbout this Structure
3ebp is a 1 chain structure with sequence from Oryctolagus cuniculus. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Tsitsanou KE, Hayes JM, Keramioti M, Mamais M, Oikonomakos NG, Kato A, Leonidas DD, Zographos SE. Sourcing the affinity of flavonoids for the glycogen phosphorylase inhibitor site via crystallography, kinetics and QM/MM-PBSA binding studies: Comparison of chrysin and flavopiridol. Food Chem Toxicol. 2012 Dec 29. pii: S0278-6915(12)00903-9. doi:, 10.1016/j.fct.2012.12.030. PMID:23279842 doi:http://dx.doi.org/10.1016/j.fct.2012.12.030
Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Oryctolagus cuniculus
- Phosphorylase
- Alexacou, K M.
- Hayes, J M.
- Leonidas, D D.
- Oikonomakos, N G.
- Tiraidis, C.
- Zographos, S E.
- Allosteric enzyme
- Carbohydrate metabolism
- Diabetes type 2
- Glycogen metabolism
- Glycogen phosphorylase
- Glycogenolysis
- Glycosyltransferase
- Nucleotide-binding
- Phosphoprotein
- Pyridoxal phosphate
- Rational inhibitor design
- Transferase-transferase inhibitor complex