1yi4: Difference between revisions

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[[Image:1yi4.gif|left|200px]]<br /><applet load="1yi4" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1yi4.gif|left|200px]]
caption="1yi4, resolution 2.400&Aring;" />
 
'''Structure of Pim-1 bound to adenosine'''<br />
{{Structure
|PDB= 1yi4 |SIZE=350|CAPTION= <scene name='initialview01'>1yi4</scene>, resolution 2.400&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ADN:ADENOSINE'>ADN</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
|GENE= PIM1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Structure of Pim-1 bound to adenosine'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1YI4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ADN:'>ADN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YI4 OCA].  
1YI4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YI4 OCA].  


==Reference==
==Reference==
Pim-1 ligand-bound structures reveal the mechanism of serine/threonine kinase inhibition by LY294002., Jacobs MD, Black J, Futer O, Swenson L, Hare B, Fleming M, Saxena K, J Biol Chem. 2005 Apr 8;280(14):13728-34. Epub 2005 Jan 17. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15657054 15657054]
Pim-1 ligand-bound structures reveal the mechanism of serine/threonine kinase inhibition by LY294002., Jacobs MD, Black J, Futer O, Swenson L, Hare B, Fleming M, Saxena K, J Biol Chem. 2005 Apr 8;280(14):13728-34. Epub 2005 Jan 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15657054 15657054]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: proto oncogene]]
[[Category: proto oncogene]]


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