1xd1: Difference between revisions

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[[Image:1xd1.gif|left|200px]]<br /><applet load="1xd1" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1xd1.gif|left|200px]]
caption="1xd1, resolution 2.2&Aring;" />
 
'''Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts'''<br />
{{Structure
|PDB= 1xd1 |SIZE=350|CAPTION= <scene name='initialview01'>1xd1</scene>, resolution 2.2&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=6SA:ACARBOSE+DERIVED+HEXASACCHARIDE'>6SA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=CL:CHLORIDE ION'>CL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Alpha-amylase Alpha-amylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.1 3.2.1.1]
|GENE= AMY2A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Acarbose Rearrangement Mechanism Implied by the Kinetic and Structural Analysis of Human Pancreatic alpha-Amylase in Complex with Analogues and Their Elongated Counterparts'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1XD1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=6SA:'>6SA</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=CL:'>CL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Alpha-amylase Alpha-amylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.1 3.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XD1 OCA].  
1XD1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XD1 OCA].  


==Reference==
==Reference==
Acarbose rearrangement mechanism implied by the kinetic and structural analysis of human pancreatic alpha-amylase in complex with analogues and their elongated counterparts., Li C, Begum A, Numao S, Park KH, Withers SG, Brayer GD, Biochemistry. 2005 Mar 8;44(9):3347-57. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15736945 15736945]
Acarbose rearrangement mechanism implied by the kinetic and structural analysis of human pancreatic alpha-amylase in complex with analogues and their elongated counterparts., Li C, Begum A, Numao S, Park KH, Withers SG, Brayer GD, Biochemistry. 2005 Mar 8;44(9):3347-57. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15736945 15736945]
[[Category: Alpha-amylase]]
[[Category: Alpha-amylase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: NAG]]
[[Category: NAG]]
[[Category: acarbose]]
[[Category: acarbose]]
[[Category: acarbose analogues]]
[[Category: acarbose analogue]]
[[Category: acarviosine]]
[[Category: acarviosine]]
[[Category: amylase]]
[[Category: amylase]]
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[[Category: structure]]
[[Category: structure]]


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