1xa5: Difference between revisions

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[[Image:1xa5.gif|left|200px]]<br /><applet load="1xa5" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1xa5.gif|left|200px]]
caption="1xa5, resolution 2.12&Aring;" />
 
'''Structure of Calmodulin in complex with KAR-2, a bis-indol alkaloid'''<br />
{{Structure
|PDB= 1xa5 |SIZE=350|CAPTION= <scene name='initialview01'>1xa5</scene>, resolution 2.12&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=KAR:3 -(BETA-CHLOROETHYL)-2 ,4 -DIOXO-3, 5 -SPIRO-OXAZOLIDINO-4-DEACETOXY-VINBLASTINE'>KAR</scene>
|ACTIVITY=
|GENE=
}}
 
'''Structure of Calmodulin in complex with KAR-2, a bis-indol alkaloid'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1XA5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=KAR:'>KAR</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XA5 OCA].  
1XA5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XA5 OCA].  


==Reference==
==Reference==
The structure of the complex of calmodulin with KAR-2: a novel mode of binding explains the unique pharmacology of the drug., Horvath I, Harmat V, Perczel A, Palfi V, Nyitray L, Nagy A, Hlavanda E, Naray-Szabo G, Ovadi J, J Biol Chem. 2005 Mar 4;280(9):8266-74. Epub 2004 Dec 13. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15596444 15596444]
The structure of the complex of calmodulin with KAR-2: a novel mode of binding explains the unique pharmacology of the drug., Horvath I, Harmat V, Perczel A, Palfi V, Nyitray L, Nagy A, Hlavanda E, Naray-Szabo G, Ovadi J, J Biol Chem. 2005 Mar 4;280(9):8266-74. Epub 2004 Dec 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15596444 15596444]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: vinca alkaloid]]
[[Category: vinca alkaloid]]


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