1xa5: Difference between revisions
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[[Image:1xa5.gif|left|200px]] | [[Image:1xa5.gif|left|200px]] | ||
'''Structure of Calmodulin in complex with KAR-2, a bis-indol alkaloid''' | {{Structure | ||
|PDB= 1xa5 |SIZE=350|CAPTION= <scene name='initialview01'>1xa5</scene>, resolution 2.12Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=KAR:3 -(BETA-CHLOROETHYL)-2 ,4 -DIOXO-3, 5 -SPIRO-OXAZOLIDINO-4-DEACETOXY-VINBLASTINE'>KAR</scene> | |||
|ACTIVITY= | |||
|GENE= | |||
}} | |||
'''Structure of Calmodulin in complex with KAR-2, a bis-indol alkaloid''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1XA5 is a [ | 1XA5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XA5 OCA]. | ||
==Reference== | ==Reference== | ||
The structure of the complex of calmodulin with KAR-2: a novel mode of binding explains the unique pharmacology of the drug., Horvath I, Harmat V, Perczel A, Palfi V, Nyitray L, Nagy A, Hlavanda E, Naray-Szabo G, Ovadi J, J Biol Chem. 2005 Mar 4;280(9):8266-74. Epub 2004 Dec 13. PMID:[http:// | The structure of the complex of calmodulin with KAR-2: a novel mode of binding explains the unique pharmacology of the drug., Horvath I, Harmat V, Perczel A, Palfi V, Nyitray L, Nagy A, Hlavanda E, Naray-Szabo G, Ovadi J, J Biol Chem. 2005 Mar 4;280(9):8266-74. Epub 2004 Dec 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15596444 15596444] | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: vinca alkaloid]] | [[Category: vinca alkaloid]] | ||
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