1x95: Difference between revisions

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[[Image:1x95.gif|left|200px]]<br /><applet load="1x95" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1x95.gif|left|200px]]
caption="1x95" />
 
'''solution structure of the B-DNA hexamer ATGCAT complexed with MLN944, a bisphenazine anticancer drug'''<br />
{{Structure
|PDB= 1x95 |SIZE=350|CAPTION= <scene name='initialview01'>1x95</scene>
|SITE=  
|LIGAND= <scene name='pdbligand=XR2:1-METHYL-9-[12-(9-METHYLPHENAZIN-10-IUM-1-YL)-12-OXO-2,11-DIAZA-5,8-DIAZONIADODEC-1-ANOYL]PHENAZIN-10-IUM'>XR2</scene>
|ACTIVITY=
|GENE=
}}
 
'''solution structure of the B-DNA hexamer ATGCAT complexed with MLN944, a bisphenazine anticancer drug'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1X95 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=XR2:'>XR2</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X95 OCA].  
1X95 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X95 OCA].  


==Reference==
==Reference==
Novel DNA bis-intercalation by MLN944, a potent clinical bisphenazine anticancer drug., Dai J, Punchihewa C, Mistry P, Ooi AT, Yang D, J Biol Chem. 2004 Oct 29;279(44):46096-103. Epub 2004 Aug 17. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15317822 15317822]
Novel DNA bis-intercalation by MLN944, a potent clinical bisphenazine anticancer drug., Dai J, Punchihewa C, Mistry P, Ooi AT, Yang D, J Biol Chem. 2004 Oct 29;279(44):46096-103. Epub 2004 Aug 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15317822 15317822]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Dai, J.]]
[[Category: Dai, J.]]
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[[Category: transcription inhibition]]
[[Category: transcription inhibition]]


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