1x97: Difference between revisions

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-[[Image:1x97.gif|left|200px]]<br /><applet load="1x97" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1x97.gif|left|200px]]
-caption="1x97, resolution 1.40&Aring;" />
-'''Crystal structure of Aldose Reductase complexed with 2R4S (Stereoisomer of Fidarestat, 2S4S)'''<br />
+ {{Structure
+|PDB= 1x97 |SIZE=350|CAPTION= <scene name='initialview01'>1x97</scene>, resolution 1.40&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene> and <scene name='pdbligand=FIR:(2R,4S)-2-AMINOFORMYL-6-FLUORO-SPIRO[CHROMAN-4,4'-IMIDAZOLIDINE]-2',5'-DIONE'>FIR</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21]
+|GENE=
+}}
+'''Crystal structure of Aldose Reductase complexed with 2R4S (Stereoisomer of Fidarestat, 2S4S)'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-X97 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAP:'>NAP</scene> and <scene name='pdbligand=FIR:'>FIR</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X97 OCA].
+X97 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1X97 OCA].
 ==Reference==
-High-resolution structures of human aldose reductase holoenzyme in complex with stereoisomers of the potent inhibitor Fidarestat: stereospecific interaction between the enzyme and a cyclic imide type inhibitor., El-Kabbani O, Darmanin C, Oka M, Schulze-Briese C, Tomizaki T, Hazemann I, Mitschler A, Podjarny A, J Med Chem. 2004 Aug 26;47(18):4530-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15317464 15317464]
+High-resolution structures of human aldose reductase holoenzyme in complex with stereoisomers of the potent inhibitor Fidarestat: stereospecific interaction between the enzyme and a cyclic imide type inhibitor., El-Kabbani O, Darmanin C, Oka M, Schulze-Briese C, Tomizaki T, Hazemann I, Mitschler A, Podjarny A, J Med Chem. 2004 Aug 26;47(18):4530-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15317464 15317464]
 [[Category: Aldehyde reductase]]
 [[Category: Homo sapiens]]
@@ Line 28: / Line 37: @@
 [[Category: the c-terminal end of the barrel]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:52:22 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:06:40 2008''