2gf2: Difference between revisions

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[[Image:2gf2.png|left|200px]]
==Crystal structure of human hydroxyisobutyrate dehydrogenase==
 
<StructureSection load='2gf2' size='340' side='right' caption='[[2gf2]], [[Resolution|resolution]] 2.38&Aring;' scene=''>
{{STRUCTURE_2gf2|  PDB=2gf2  |  SCENE=  }}
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2gf2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2GF2 FirstGlance]. <br>
===Crystal structure of human hydroxyisobutyrate dehydrogenase===
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HIBADH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
 
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-hydroxyisobutyrate_dehydrogenase 3-hydroxyisobutyrate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.31 1.1.1.31] </span></td></tr>
 
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gf2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gf2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2gf2 RCSB], [http://www.ebi.ac.uk/pdbsum/2gf2 PDBsum]</span></td></tr>
==About this Structure==
<table>
[[2gf2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GF2 OCA].  
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gf/2gf2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: 3-hydroxyisobutyrate dehydrogenase]]
[[Category: 3-hydroxyisobutyrate dehydrogenase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]

Revision as of 11:36, 30 September 2014

Crystal structure of human hydroxyisobutyrate dehydrogenaseCrystal structure of human hydroxyisobutyrate dehydrogenase

Structural highlights

2gf2 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Gene:HIBADH (Homo sapiens)
Activity:3-hydroxyisobutyrate dehydrogenase, with EC number 1.1.1.31
Resources:FirstGlance, OCA, RCSB, PDBsum

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

2gf2, resolution 2.38Å

Drag the structure with the mouse to rotate

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OCA
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