Ferrochelatase: Difference between revisions

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Revision as of 11:38, 7 January 2013 view source Michal Harel (talk \| contribs) 31,761 edits No edit summary ← Older edit		Revision as of 11:39, 7 January 2013 view source Michal Harel (talk \| contribs) 31,761 edits No edit summary Newer edit →
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	{{STRUCTURE_2qd3\| PDB=2qd3 \| SIZE=400\| SCENE= \|right\|CAPTION=Human ferrochelatase with protoporpohyrin and Fe2S2 cluster, [[2qd3]] }}		{{STRUCTURE_2qd3\| PDB=2qd3 \| SIZE=400\| SCENE= \|right\|CAPTION=Human ferrochelatase dimer with protoporpohyrin and Fe2S2 cluster, [[2qd3]] }}

	'''Ferrochelatase''' (FECH) catalyzes the last step in the formation of heme. FECH adds Fe+2 to protoporphyrin IX converting it to protoheme. The human FECH is a homodimer containing 2 similar domains and an iron-sulfur cluster. Defective FECH is the cause of porphyria.		'''Ferrochelatase''' (FECH) catalyzes the last step in the formation of heme. FECH adds Fe+2 to protoporphyrin IX converting it to protoheme. The human FECH is a homodimer containing 2 similar domains and an iron-sulfur cluster. Defective FECH is the cause of porphyria.