1uy8: Difference between revisions

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[[Image:1uy8.jpg|left|200px]]<br /><applet load="1uy8" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1uy8.jpg|left|200px]]
caption="1uy8, resolution 1.98&Aring;" />
 
'''HUMAN HSP90-ALPHA WITH 9-BUTYL-8-(3-TRIMETHOXY-BENZYL)-9H-PURIN-6YLAMINE'''<br />
{{Structure
|PDB= 1uy8 |SIZE=350|CAPTION= <scene name='initialview01'>1uy8</scene>, resolution 1.98&Aring;
|SITE= <scene name='pdbsite=AC1:Pu5+Binding+Site+For+Chain+A'>AC1</scene>
|LIGAND= <scene name='pdbligand=PU5:9-BUTYL-8-(3-METHOXYBENZYL)-9H-PURIN-6-AMINE'>PU5</scene>
|ACTIVITY=
|GENE=
}}
 
'''HUMAN HSP90-ALPHA WITH 9-BUTYL-8-(3-TRIMETHOXY-BENZYL)-9H-PURIN-6YLAMINE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1UY8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=PU5:'>PU5</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Site: <scene name='pdbsite=AC1:Pu5+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UY8 OCA].  
1UY8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UY8 OCA].  


==Reference==
==Reference==
Structure-activity relationships in purine-based inhibitor binding to HSP90 isoforms., Wright L, Barril X, Dymock B, Sheridan L, Surgenor A, Beswick M, Drysdale M, Collier A, Massey A, Davies N, Fink A, Fromont C, Aherne W, Boxall K, Sharp S, Workman P, Hubbard RE, Chem Biol. 2004 Jun;11(6):775-85. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15217611 15217611]
Structure-activity relationships in purine-based inhibitor binding to HSP90 isoforms., Wright L, Barril X, Dymock B, Sheridan L, Surgenor A, Beswick M, Drysdale M, Collier A, Massey A, Davies N, Fink A, Fromont C, Aherne W, Boxall K, Sharp S, Workman P, Hubbard RE, Chem Biol. 2004 Jun;11(6):775-85. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15217611 15217611]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: pu5]]
[[Category: pu5]]


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