1utz: Difference between revisions
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[[Image:1utz.jpg|left|200px]] | [[Image:1utz.jpg|left|200px]] | ||
'''CRYSTAL STRUCTURE OF MMP-12 COMPLEXED TO (2R)-3-({[4-[(PYRI DIN-4-YL)PHENYL]-THIEN-2-YL}CARBOXAMIDO)(PHENYL)PROPANOIC ACID''' | {{Structure | ||
|PDB= 1utz |SIZE=350|CAPTION= <scene name='initialview01'>1utz</scene>, resolution 2.5Å | |||
|SITE= <scene name='pdbsite=ZN2:Ca+Binding+Site+For+Chain+B'>ZN2</scene> | |||
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PF3:(2R)-3-({[4-[(PYRIDIN-4-YL)PHENYL]-THIEN-2-YL}CARBOXAMIDO)(PHENYL)PROPANOIC+ACID'>PF3</scene> and <scene name='pdbligand=HAE:ACETOHYDROXAMIC ACID'>HAE</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65] | |||
|GENE= | |||
}} | |||
'''CRYSTAL STRUCTURE OF MMP-12 COMPLEXED TO (2R)-3-({[4-[(PYRI DIN-4-YL)PHENYL]-THIEN-2-YL}CARBOXAMIDO)(PHENYL)PROPANOIC ACID''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1UTZ is a [ | 1UTZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UTZ OCA]. | ||
==Reference== | ==Reference== | ||
Crystal structures of novel non-peptidic, non-zinc chelating inhibitors bound to MMP-12., Morales R, Perrier S, Florent JM, Beltra J, Dufour S, De Mendez I, Manceau P, Tertre A, Moreau F, Compere D, Dublanchet AC, O'Gara M, J Mol Biol. 2004 Aug 20;341(4):1063-76. PMID:[http:// | Crystal structures of novel non-peptidic, non-zinc chelating inhibitors bound to MMP-12., Morales R, Perrier S, Florent JM, Beltra J, Dufour S, De Mendez I, Manceau P, Tertre A, Moreau F, Compere D, Dublanchet AC, O'Gara M, J Mol Biol. 2004 Aug 20;341(4):1063-76. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15289103 15289103] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Macrophage elastase]] | [[Category: Macrophage elastase]] | ||
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[[Category: non-zinc chelator]] | [[Category: non-zinc chelator]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:36:49 2008'' |