Sandbox Reserved 708: Difference between revisions
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== Description == | == Description == | ||
The Glycogen Synthase Kinase 3 beta- GSK-3β, also known as the tau protein kinase I, is a serine protein kinase that participates in many different pathways regulating critical cellular functions as structure, gene expression, mobility, and apoptosis,<ref name="SINR"> "Structural insight into nucleotide recognition in tau-protein kinase I/glycogen synthase kinase 3 beta." | The Glycogen Synthase Kinase 3 beta- GSK-3β, also known as the tau-protein-kinase I, is a serine protein kinase that participates in many different pathways regulating critical cellular functions as structure, gene expression, mobility, and apoptosis,<ref name="SINR"> "Structural insight into nucleotide recognition in tau-protein kinase I/glycogen synthase kinase 3 beta." | ||
Aoki, M., Yokota, T., Sugiura, I., Sasaki, C., Hasegawa, T., Okumura, C., Ishiguro, K., Kohno, T., Sugio, S., Matsuzaki, T. | Aoki, M., Yokota, T., Sugiura, I., Sasaki, C., Hasegawa, T., Okumura, C., Ishiguro, K., Kohno, T., Sugio, S., Matsuzaki, T. | ||
Journal: (2004) Acta Crystallogr.,Sect.D60: 439-446</ref>. GSK-3 phosphorylates a large number of substrates and is himself regulated by phosphorylation,<ref name="GSK3 IDT"> "Glycogen Synthase Kinase-3 (GSK3): Inflammation, Diseases, and Therapeutics." Richard S. Jope,* Christopher J. Yuskaitis, and Eléonore Beurel Neurochem Res. 2007; 32(4-5): 577-595.</ref>. | Journal: (2004) Acta Crystallogr.,Sect.D60: 439-446</ref>. GSK-3 phosphorylates a large number of substrates and is himself regulated by phosphorylation,<ref name="GSK3 IDT"> "Glycogen Synthase Kinase-3 (GSK3): Inflammation, Diseases, and Therapeutics." Richard S. Jope,* Christopher J. Yuskaitis, and Eléonore Beurel Neurochem Res. 2007; 32(4-5): 577-595.</ref>. | ||