1tno: Difference between revisions
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[[Image:1tno.gif|left|200px]]< | [[Image:1tno.gif|left|200px]] | ||
'''Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a KKKSKTKCVIM Peptide Derived from K-Ras4B''' | {{Structure | ||
|PDB= 1tno |SIZE=350|CAPTION= <scene name='initialview01'>1tno</scene>, resolution 2.70Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene> and <scene name='pdbligand=MGM:2-[METHYL-(5-GERANYL-4-METHYL-PENT-3-ENYL)-AMINO]-ETHYL-DIPHOSPHATE'>MGM</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Protein_geranylgeranyltransferase_type_I Protein geranylgeranyltransferase type I], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.59 2.5.1.59] | |||
|GENE= FNTA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus]), PGGT1B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus]) | |||
}} | |||
'''Rat Protein Geranylgeranyltransferase Type-I Complexed with a GGPP analog and a KKKSKTKCVIM Peptide Derived from K-Ras4B''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1TNO is a [ | 1TNO is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TNO OCA]. | ||
==Reference== | ==Reference== | ||
Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity., Reid TS, Terry KL, Casey PJ, Beese LS, J Mol Biol. 2004 Oct 15;343(2):417-33. PMID:[http:// | Crystallographic analysis of CaaX prenyltransferases complexed with substrates defines rules of protein substrate selectivity., Reid TS, Terry KL, Casey PJ, Beese LS, J Mol Biol. 2004 Oct 15;343(2):417-33. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15451670 15451670] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Protein geranylgeranyltransferase type I]] | [[Category: Protein geranylgeranyltransferase type I]] | ||
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[[Category: geranylgeranyltransferase type-i]] | [[Category: geranylgeranyltransferase type-i]] | ||
[[Category: ggtase-i]] | [[Category: ggtase-i]] | ||
[[Category: k- | [[Category: k-ra]] | ||
[[Category: lipid modification]] | [[Category: lipid modification]] | ||
[[Category: prenylation]] | [[Category: prenylation]] | ||
[[Category: prenyltransferase]] | [[Category: prenyltransferase]] | ||
[[Category: | [[Category: ra]] | ||
[[Category: substrate selectivity]] | [[Category: substrate selectivity]] | ||
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