Sandbox Reserved 712: Difference between revisions
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[[HIV-1 protease]]s are essential for HIV to survive. They are small enzymes, which are made out of two identical, 99 amino acids long, protein chains. | [[HIV-1 protease]]s are essential for HIV to survive. They are small enzymes, which are made out of two identical, 99 amino acids long, protein chains. | ||
These chains form a tunnel, which is covered by so called (flexible) "flaps". The flaps's function is to "wrap around" the substrate-protein and holding it close to the tunnel and therefore to the active site. | These chains form a tunnel, which is covered by so called (flexible) "flaps". The flaps's function is to "wrap around" the substrate-protein and holding it close to the tunnel and therefore to the active site. | ||
The <scene name='Sandbox_Reserved_712/Activesite/2'>active site</scene> is located in the tunnel. The <scene name='Sandbox_Reserved_712/Activesite/2'>active site</scene> uses water molecules to break the subrate-protein chain. | The <scene name='Sandbox_Reserved_712/Activesite/2'>active site</scene> is located in the tunnel. The <scene name='Sandbox_Reserved_712/Activesite/2'>active site</scene> uses water molecules to break the subrate-protein chain. Its most important residues are two aspartate amino acids. | ||
Inhibitors occupie similar positions as the natural substrate-protein chains. | Inhibitors occupie similar positions as the natural substrate-protein chains. | ||