1syh: Difference between revisions

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[[Image:1syh.gif|left|200px]]<br /><applet load="1syh" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1syh.gif|left|200px]]
caption="1syh, resolution 1.8&Aring;" />
 
'''X-RAY STRUCTURE OF THE GLUR2 LIGAND-BINDING CORE (S1S2J) IN COMPLEX WITH (S)-CPW399 AT 1.85 A RESOLUTION.'''<br />
{{Structure
|PDB= 1syh |SIZE=350|CAPTION= <scene name='initialview01'>1syh</scene>, resolution 1.8&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CPW:(S)-2-AMINO-3-(1,3,5,7-PENTAHYDRO-2,4-DIOXO-CYCLOPENTA[E]PYRIMIDIN-1-YL) PROIONIC ACID'>CPW</scene>
|ACTIVITY=
|GENE= GRIA2, GLUR2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])
}}
 
'''X-RAY STRUCTURE OF THE GLUR2 LIGAND-BINDING CORE (S1S2J) IN COMPLEX WITH (S)-CPW399 AT 1.85 A RESOLUTION.'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1SYH is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=CPW:'>CPW</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SYH OCA].  
1SYH is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SYH OCA].  


==Reference==
==Reference==
Tyr702 is an important determinant of agonist binding and domain closure of the ligand-binding core of GluR2., Frandsen A, Pickering DS, Vestergaard B, Kasper C, Nielsen BB, Greenwood JR, Campiani G, Fattorusso C, Gajhede M, Schousboe A, Kastrup JS, Mol Pharmacol. 2005 Mar;67(3):703-13. Epub 2004 Dec 9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15591246 15591246]
Tyr702 is an important determinant of agonist binding and domain closure of the ligand-binding core of GluR2., Frandsen A, Pickering DS, Vestergaard B, Kasper C, Nielsen BB, Greenwood JR, Campiani G, Fattorusso C, Gajhede M, Schousboe A, Kastrup JS, Mol Pharmacol. 2005 Mar;67(3):703-13. Epub 2004 Dec 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15591246 15591246]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: ligand-binding core]]
[[Category: ligand-binding core]]


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