1slv: Difference between revisions

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[[Image:1slv.gif|left|200px]]<br /><applet load="1slv" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1slv.gif|left|200px]]
caption="1slv, resolution 2.3&Aring;" />
 
'''RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN; COPPER-BOUND'''<br />
{{Structure
|PDB= 1slv |SIZE=350|CAPTION= <scene name='initialview01'>1slv</scene>, resolution 2.3&Aring;
|SITE= <scene name='pdbsite=CU1:Cu+Binding+Site'>CU1</scene>
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene> and <scene name='pdbligand=CU:COPPER (II) ION'>CU</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4]
|GENE= RAT ANIONIC TRYPSIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli]), RAT ANIONIC TRYPSIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])
}}
 
'''RAT ANIONIC N143H, E151H TRYPSIN COMPLEXED TO A86H ECOTIN; COPPER-BOUND'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1SLV is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=ACT:'>ACT</scene> and <scene name='pdbligand=CU:'>CU</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] Known structural/functional Site: <scene name='pdbsite=CU1:Cu+Binding+Site'>CU1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SLV OCA].  
1SLV is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SLV OCA].  


==Reference==
==Reference==
X-ray structures of a designed binding site in trypsin show metal-dependent geometry., Brinen LS, Willett WS, Craik CS, Fletterick RJ, Biochemistry. 1996 May 14;35(19):5999-6009. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8634241 8634241]
X-ray structures of a designed binding site in trypsin show metal-dependent geometry., Brinen LS, Willett WS, Craik CS, Fletterick RJ, Biochemistry. 1996 May 14;35(19):5999-6009. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8634241 8634241]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: complex]]
[[Category: complex]]
[[Category: inhibitor]]
[[Category: inhibitor]]
[[Category: metal binding sites]]
[[Category: metal binding site]]
[[Category: metalloproteins]]
[[Category: metalloprotein]]
[[Category: protease-substrate interactions]]
[[Category: protease-substrate interaction]]
[[Category: protein engineering]]
[[Category: protein engineering]]
[[Category: serine protease]]
[[Category: serine protease]]


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