1rt3: Difference between revisions

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OCA

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-[[Image:1rt3.gif|left|200px]]<br /><applet load="1rt3" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1rt3.gif|left|200px]]
-caption="1rt3, resolution 3.0&Aring;" />
-'''AZT DRUG RESISTANT HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH 1051U91'''<br />
+ {{Structure
+|PDB= 1rt3 |SIZE=350|CAPTION= <scene name='initialview01'>1rt3</scene>, resolution 3.0&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=U05:6,11-DIHYDRO-11-ETHYL-6-METHYL-9-NITRO-5H-PYRIDO[2,3-B][1,5]BENZODIAZEPIN-5-ONE'>U05</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49]
+|GENE= POL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])
+}}
+'''AZT DRUG RESISTANT HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH 1051U91'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-RT3 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=U05:'>U05</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RT3 OCA].
+RT3 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RT3 OCA].
 ==Reference==
-'-Azido-3'-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes., Ren J, Esnouf RM, Hopkins AL, Jones EY, Kirby I, Keeling J, Ross CK, Larder BA, Stuart DI, Stammers DK, Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9518-23. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9689112 9689112]
+'-Azido-3'-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes., Ren J, Esnouf RM, Hopkins AL, Jones EY, Kirby I, Keeling J, Ross CK, Larder BA, Stuart DI, Stammers DK, Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9518-23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9689112 9689112]
 [[Category: Human immunodeficiency virus 1]]
 [[Category: Protein complex]]
@@ Line 18: / Line 27: @@
 [[Category: Stuart, D I.]]
 [[Category: U05]]
-[[Category: aids]]
+[[Category: aid]]
 [[Category: drug resistance mutation]]
 [[Category: hiv-1 reverse transcriptase]]
@@ Line 24: / Line 33: @@
 [[Category: nucleotidyltransferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:54:12 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:55:48 2008''