3uqx: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
[[ | ==Crystal structure of BACE1 with its inhibitor== | ||
<StructureSection load='3uqx' size='340' side='right' caption='[[3uqx]], [[Resolution|resolution]] 1.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3uqx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UQX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3UQX FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=URE:UREA'>URE</scene>, <scene name='pdbligand=ZPZ:N-[(1R)-1-(4-FLUOROPHENYL)ETHYL]-N-[(2S,3S)-3-HYDROXY-4-{4-[(1S)-1-HYDROXYETHYL]-1H-1,2,3-TRIAZOL-1-YL}-1-PHENYLBUTAN-2-YL]-5-[METHYL(METHYLSULFONYL)AMINO]BENZENE-1,3-DICARBOXAMIDE'>ZPZ</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3uqp|3uqp]], [[4dv9|4dv9]], [[3uqr|3uqr]], [[4dvf|4dvf]], [[3uqu|3uqu]], [[3uqw|3uqw]]</td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BACE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Memapsin_2 Memapsin 2], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.46 3.4.23.46] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3uqx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uqx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3uqx RCSB], [http://www.ebi.ac.uk/pdbsum/3uqx PDBsum]</span></td></tr> | |||
</table> | |||
==See Also== | |||
*[[Beta secretase|Beta secretase]] | |||
__TOC__ | |||
</StructureSection> | |||
== | |||
[[ | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Memapsin 2]] | [[Category: Memapsin 2]] | ||
[[Category: Chen, T T | [[Category: Chen, T T]] | ||
[[Category: Chen, W Y | [[Category: Chen, W Y]] | ||
[[Category: Xu, Y C | [[Category: Xu, Y C]] | ||
[[Category: Bace1]] | [[Category: Bace1]] | ||
[[Category: Beta-secretase]] | [[Category: Beta-secretase]] | ||
[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
Revision as of 18:25, 9 December 2014
Crystal structure of BACE1 with its inhibitorCrystal structure of BACE1 with its inhibitor
Structural highlights
See Also |
| ||||||||||||||||||||||