Severin: Difference between revisions

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[[Image:Severin.png|left|200px|thumb|Crystal Structure of Human Severin, [[3fg6]]]]
[[Image:Severin.png|left|200px|thumb|Crystal Structure of Human Severin, [[3fg6]]]]
{{STRUCTURE_1svy| PDB=1svy  |  SCENE= |CAPTION=Severin, [[1svy]] }}
{{STRUCTURE_1svy| PDB=1svy  |  SCENE= |CAPTION=Severin domain 2 complex with Ca+2 (green) and Na+ (purple) ions [[1svy]] }}


[[Severin]] is a calcium-activated protein which binds actin. The images at the top and at the right correspond to one representative severin structure, ''i.e.'' the human severin ([[3fg6]]). It nucleates actin assembly, severes F-actin  and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins. It is named Adseverin and Scinderin as well. The image at the right is the severin with <scene name='Severin/Cv/5'>calcium ions</scene> (<font color='lime'><b>colored lime</b></font>).   
[[Severin]] is a calcium-activated protein which binds actin. The images at the top and at the right correspond to one representative severin structure, ''i.e.'' the human severin ([[3fg6]]). It nucleates actin assembly, severes F-actin  and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins. It is named Adseverin and Scinderin as well. The image at the right is the severin with <scene name='Severin/Cv/5'>calcium ions</scene> (<font color='lime'><b>colored lime</b></font>).   

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Alexander Berchansky, Michal Harel, Jaime Prilusky