1brq: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-[[Image:1brq.png|left|200px]]
 {{STRUCTURE_1brq|  PDB=1brq  |  SCENE=  }}
+===CRYSTAL STRUCTURE OF THE TRIGONAL FORM OF HUMAN PLASMA RETINOL-BINDING PROTEIN AT 2.5 ANGSTROMS RESOLUTION===
+{{ABSTRACT_PUBMED_8464067}}
-===CRYSTAL STRUCTURE OF THE TRIGONAL FORM OF HUMAN PLASMA RETINOL-BINDING PROTEIN AT 2.5 ANGSTROMS RESOLUTION===
+==Disease==
+[[http://www.uniprot.org/uniprot/RET4_HUMAN RET4_HUMAN]] Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [MIM:[http://omim.org/entry/180250 180250]]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.
-{{ABSTRACT_PUBMED_8464067}}
+==Function==
+[[http://www.uniprot.org/uniprot/RET4_HUMAN RET4_HUMAN]] Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.
 ==About this Structure==
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 ==Reference==
-<ref group="xtra">PMID:008464067</ref><references group="xtra"/>
+<ref group="xtra">PMID:008464067</ref><references group="xtra"/><references/>
 [[Category: Homo sapiens]]
 [[Category: Monaco, H L.]]
 [[Category: Zanotti, G.]]
 [[Category: Retinol transport]]