2c7p: Difference between revisions
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{{STRUCTURE_2c7p| PDB=2c7p | SCENE= }} | {{STRUCTURE_2c7p| PDB=2c7p | SCENE= }} | ||
===HhaI DNA methyltransferase complex with oligonucleotide containing 2- aminopurine opposite to the target base (GCGC:GMPC) and SAH=== | |||
{{ABSTRACT_PUBMED_16340006}} | |||
=== | ==Function== | ||
[[http://www.uniprot.org/uniprot/MTH1_HAEPH MTH1_HAEPH]] This methylase recognizes the double-stranded sequence GCGC, causes specific methylation on C-2 on both strands, and protects the DNA from cleavage by the HhaI endonuclease. | |||
==About this Structure== | ==About this Structure== | ||
[[2c7p]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[2c7p]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_x"_pritchett_and_stillman_1919 "bacillus x" pritchett and stillman 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C7P OCA]. | ||
==See Also== | ==See Also== | ||
*[[DNA methyltransferase|DNA methyltransferase]] | *[[DNA methyltransferase|DNA methyltransferase]] | ||
*[[HhaI DNA methyltransferase|HhaI DNA methyltransferase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:016340006</ref><references group="xtra"/> | <ref group="xtra">PMID:016340006</ref><references group="xtra"/><references/> | ||
[[Category: | [[Category: Bacillus x pritchett and stillman 1919]] | ||
[[Category: Daujotyte, D.]] | [[Category: Daujotyte, D.]] | ||
[[Category: Dryden, D T.F.]] | |||
[[Category: Grazulis, S.]] | [[Category: Grazulis, S.]] | ||
[[Category: Jones, A C.]] | |||
[[Category: Klimasauskas, S.]] | |||
[[Category: Magennis, S W.]] | |||
[[Category: Neely, R K.]] | |||
[[Category: Base flipping]] | [[Category: Base flipping]] | ||
[[Category: Restriction system]] | [[Category: Restriction system]] | ||
[[Category: Transferase]] | [[Category: Transferase-dna complex]] | ||
Revision as of 09:28, 29 January 2014
HhaI DNA methyltransferase complex with oligonucleotide containing 2- aminopurine opposite to the target base (GCGC:GMPC) and SAHHhaI DNA methyltransferase complex with oligonucleotide containing 2- aminopurine opposite to the target base (GCGC:GMPC) and SAH
Template:ABSTRACT PUBMED 16340006
FunctionFunction
[MTH1_HAEPH] This methylase recognizes the double-stranded sequence GCGC, causes specific methylation on C-2 on both strands, and protects the DNA from cleavage by the HhaI endonuclease.
About this StructureAbout this Structure
2c7p is a 3 chain structure with sequence from "bacillus_x"_pritchett_and_stillman_1919 "bacillus x" pritchett and stillman 1919. Full crystallographic information is available from OCA.
See AlsoSee Also
ReferenceReference
- ↑ Neely RK, Daujotyte D, Grazulis S, Magennis SW, Dryden DT, Klimasauskas S, Jones AC. Time-resolved fluorescence of 2-aminopurine as a probe of base flipping in M.HhaI-DNA complexes. Nucleic Acids Res. 2005 Dec 9;33(22):6953-60. Print 2005. PMID:16340006 doi:http://dx.doi.org/33/22/6953