1nvw: Difference between revisions
No edit summary |
No edit summary |
||
Line 1: | Line 1: | ||
[[Image:1nvw.jpg|left|200px]] | [[Image:1nvw.jpg|left|200px]] | ||
'''Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS''' | {{Structure | ||
|PDB= 1nvw |SIZE=350|CAPTION= <scene name='initialview01'>1nvw</scene>, resolution 2.70Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> and <scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER'>GNP</scene> | |||
|ACTIVITY= | |||
|GENE= HRAS OR HRAS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), SOS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS''' | |||
==Overview== | ==Overview== | ||
Line 10: | Line 19: | ||
==About this Structure== | ==About this Structure== | ||
1NVW is a [ | 1NVW is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NVW OCA]. | ||
==Reference== | ==Reference== | ||
Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS., Margarit SM, Sondermann H, Hall BE, Nagar B, Hoelz A, Pirruccello M, Bar-Sagi D, Kuriyan J, Cell. 2003 Mar 7;112(5):685-95. PMID:[http:// | Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS., Margarit SM, Sondermann H, Hall BE, Nagar B, Hoelz A, Pirruccello M, Bar-Sagi D, Kuriyan J, Cell. 2003 Mar 7;112(5):685-95. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12628188 12628188] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
Line 31: | Line 40: | ||
[[Category: proto-oncogene]] | [[Category: proto-oncogene]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:02:23 2008'' |