1nvw: Difference between revisions

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[[Image:1nvw.jpg|left|200px]]<br /><applet load="1nvw" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1nvw.jpg|left|200px]]
caption="1nvw, resolution 2.70&Aring;" />
 
'''Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS'''<br />
{{Structure
|PDB= 1nvw |SIZE=350|CAPTION= <scene name='initialview01'>1nvw</scene>, resolution 2.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> and <scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER'>GNP</scene>
|ACTIVITY=
|GENE= HRAS OR HRAS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), SOS1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Structural evidence for feedback activation by RasGTP of the Ras-specific nucleotide exchange factor SOS'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1NVW is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=PO4:'>PO4</scene> and <scene name='pdbligand=GNP:'>GNP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NVW OCA].  
1NVW is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NVW OCA].  


==Reference==
==Reference==
Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS., Margarit SM, Sondermann H, Hall BE, Nagar B, Hoelz A, Pirruccello M, Bar-Sagi D, Kuriyan J, Cell. 2003 Mar 7;112(5):685-95. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12628188 12628188]
Structural evidence for feedback activation by Ras.GTP of the Ras-specific nucleotide exchange factor SOS., Margarit SM, Sondermann H, Hall BE, Nagar B, Hoelz A, Pirruccello M, Bar-Sagi D, Kuriyan J, Cell. 2003 Mar 7;112(5):685-95. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12628188 12628188]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: proto-oncogene]]
[[Category: proto-oncogene]]


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