3ecs: Difference between revisions

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[[Image:3ecs.png|left|200px]]
{{STRUCTURE_3ecs|  PDB=3ecs  |  SCENE=  }}  
{{STRUCTURE_3ecs|  PDB=3ecs  |  SCENE=  }}  
===Crystal structure of human eIF2B alpha===
{{ABSTRACT_PUBMED_19631657}}


===Crystal structure of human eIF2B alpha===
==Disease==
[[http://www.uniprot.org/uniprot/EI2BA_HUMAN EI2BA_HUMAN]] Cree leukoencephalopathy;Late infantile CACH syndrome;Ovarioleukodystrophy. The disease is caused by mutations affecting the gene represented in this entry.


{{ABSTRACT_PUBMED_19631657}}
==Function==
[[http://www.uniprot.org/uniprot/EI2BA_HUMAN EI2BA_HUMAN]] Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.


==About this Structure==
==About this Structure==
[[3ecs]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ECS OCA].  
[[3ecs]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ECS OCA].  


==See Also==
==See Also==
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==Reference==
==Reference==
<ref group="xtra">PMID:019631657</ref><references group="xtra"/>
<ref group="xtra">PMID:019631657</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Hiyama, T B.]]
[[Category: Hiyama, T B.]]
[[Category: Ito, T.]]
[[Category: Ito, T.]]

Revision as of 11:00, 5 February 2014

Template:STRUCTURE 3ecs

Crystal structure of human eIF2B alphaCrystal structure of human eIF2B alpha

Template:ABSTRACT PUBMED 19631657

DiseaseDisease

[EI2BA_HUMAN] Cree leukoencephalopathy;Late infantile CACH syndrome;Ovarioleukodystrophy. The disease is caused by mutations affecting the gene represented in this entry.

FunctionFunction

[EI2BA_HUMAN] Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.

About this StructureAbout this Structure

3ecs is a 8 chain structure with sequence from Human. Full crystallographic information is available from OCA.

See AlsoSee Also

ReferenceReference

[xtra 1]

  1. Hiyama TB, Ito T, Imataka H, Yokoyama S. Crystal structure of the alpha subunit of human translation initiation factor 2B. J Mol Biol. 2009 Oct 2;392(4):937-51. Epub 2009 Jul 23. PMID:19631657 doi:10.1016/j.jmb.2009.07.054

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