1nq0: Difference between revisions

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OCA

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-[[Image:1nq0.jpg|left|200px]]<br /><applet load="1nq0" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1nq0.jpg|left|200px]]
-caption="1nq0, resolution 2.40&Aring;" />
-'''TR Receptor Mutations Conferring Hormone Resistance and Reduced Corepressor Release Exhibit Decreased Stability in the Nterminal LBD'''<br />
+ {{Structure
+|PDB= 1nq0 |SIZE=350|CAPTION= <scene name='initialview01'>1nq0</scene>, resolution 2.40&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=4HY:[4-(4-HYDROXY-3-IODO-PHENOXY)-3,5-DIIODO-PHENYL]-ACETIC+ACID'>4HY</scene> and <scene name='pdbligand=ARS:ARSENIC'>ARS</scene>
+|ACTIVITY=
+|GENE= THRB OR NR1A2 OR ERBA2 OR THR1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+}}
+'''TR Receptor Mutations Conferring Hormone Resistance and Reduced Corepressor Release Exhibit Decreased Stability in the Nterminal LBD'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-NQ0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=4HY:'>4HY</scene> and <scene name='pdbligand=ARS:'>ARS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NQ0 OCA].
+NQ0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NQ0 OCA].
 ==Reference==
-Thyroid hormone receptor-beta mutations conferring hormone resistance and reduced corepressor release exhibit decreased stability in the N-terminal ligand-binding domain., Huber BR, Desclozeaux M, West BL, Cunha-Lima ST, Nguyen HT, Baxter JD, Ingraham HA, Fletterick RJ, Mol Endocrinol. 2003 Jan;17(1):107-16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12511610 12511610]
+Thyroid hormone receptor-beta mutations conferring hormone resistance and reduced corepressor release exhibit decreased stability in the N-terminal ligand-binding domain., Huber BR, Desclozeaux M, West BL, Cunha-Lima ST, Nguyen HT, Baxter JD, Ingraham HA, Fletterick RJ, Mol Endocrinol. 2003 Jan;17(1):107-16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12511610 12511610]
 [[Category: Homo sapiens]]
 [[Category: Single protein]]
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 [[Category: thyroid hormone receptor]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:08:46 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:00:15 2008''