3b7x: Difference between revisions
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{{STRUCTURE_3b7x| PDB=3b7x | SCENE= }} | {{STRUCTURE_3b7x| PDB=3b7x | SCENE= }} | ||
===Crystal structure of human FK506-Binding Protein 6=== | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/FKBP6_HUMAN FKBP6_HUMAN]] Note=FKBP6 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of FKBP6 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease. | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/FKBP6_HUMAN FKBP6_HUMAN]] PPIases accelerate the folding of proteins. | |||
==About this Structure== | ==About this Structure== | ||
Revision as of 22:22, 24 March 2013
Crystal structure of human FK506-Binding Protein 6Crystal structure of human FK506-Binding Protein 6
DiseaseDisease
[FKBP6_HUMAN] Note=FKBP6 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of FKBP6 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
FunctionFunction
[FKBP6_HUMAN] PPIases accelerate the folding of proteins.
About this StructureAbout this Structure
3b7x is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.