1r55: Difference between revisions
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{{STRUCTURE_1r55| PDB=1r55 | SCENE= }} | {{STRUCTURE_1r55| PDB=1r55 | SCENE= }} | ||
===Crystal structure of the catalytic domain of human ADAM 33=== | ===Crystal structure of the catalytic domain of human ADAM 33=== | ||
{{ABSTRACT_PUBMED_14659745}} | |||
==Disease== | |||
[[http://www.uniprot.org/uniprot/ADA33_HUMAN ADA33_HUMAN]] Genetic variations in ADAM33 are associated with susceptibility to asthma (ASTHMA) [MIM:[http://omim.org/entry/600807 600807]]. The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi.<ref>PMID:12110844</ref><ref>PMID:16773130</ref><ref>PMID:19237393</ref> | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:014659745</ref><references group="xtra"/> | <ref group="xtra">PMID:014659745</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Hammond, G.]] | [[Category: Hammond, G.]] | ||