1nhw: Difference between revisions

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[[Image:1nhw.gif|left|200px]]<br /><applet load="1nhw" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1nhw.gif|left|200px]]
caption="1nhw, resolution 2.35&Aring;" />
 
'''Crystal Structure Analysis of Plasmodium falciparum enoyl-acyl-carrier-protein reductase'''<br />
{{Structure
|PDB= 1nhw |SIZE=350|CAPTION= <scene name='initialview01'>1nhw</scene>, resolution 2.35&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene> and <scene name='pdbligand=TCC:2-(2,4-DICHLORO-PHENYLAMINO)-PHENOL'>TCC</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9]
|GENE=
}}
 
'''Crystal Structure Analysis of Plasmodium falciparum enoyl-acyl-carrier-protein reductase'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1NHW is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum] with <scene name='pdbligand=NAD:'>NAD</scene> and <scene name='pdbligand=TCC:'>TCC</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Enoyl-[acyl-carrier-protein]_reductase_(NADH) Enoyl-[acyl-carrier-protein] reductase (NADH)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.1.9 1.3.1.9] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NHW OCA].  
1NHW is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NHW OCA].  


==Reference==
==Reference==
Structural elucidation of the specificity of the antibacterial agent triclosan for malarial enoyl acyl carrier protein reductase., Perozzo R, Kuo M, Sidhu AS, Valiyaveettil JT, Bittman R, Jacobs WR Jr, Fidock DA, Sacchettini JC, J Biol Chem. 2002 Apr 12;277(15):13106-14. Epub 2002 Jan 15. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11792710 11792710]
Structural elucidation of the specificity of the antibacterial agent triclosan for malarial enoyl acyl carrier protein reductase., Perozzo R, Kuo M, Sidhu AS, Valiyaveettil JT, Bittman R, Jacobs WR Jr, Fidock DA, Sacchettini JC, J Biol Chem. 2002 Apr 12;277(15):13106-14. Epub 2002 Jan 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11792710 11792710]
[[Category: Enoyl-[acyl-carrier-protein] reductase (NADH)]]
[[Category: Enoyl-[acyl-carrier-protein] reductase (NADH)]]
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
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[[Category: short chain dehydrogenase reductase]]
[[Category: short chain dehydrogenase reductase]]


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