3t3h: Difference between revisions
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{{STRUCTURE_3t3h| PDB=3t3h | SCENE= }} | {{STRUCTURE_3t3h| PDB=3t3h | SCENE= }} | ||
===Glycogen Phosphorylase b in complex with GlcIU=== | ===Glycogen Phosphorylase b in complex with GlcIU=== | ||
{{ABSTRACT_PUBMED_22267166}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PYGM_RABIT PYGM_RABIT]] Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. | |||
==About this Structure== | ==About this Structure== | ||
[[3t3h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T3H OCA]. | [[3t3h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T3H OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:022267166</ref><references group="xtra"/> | <ref group="xtra">PMID:022267166</ref><references group="xtra"/><references/> | ||
[[Category: Oryctolagus cuniculus]] | [[Category: Oryctolagus cuniculus]] | ||
[[Category: Phosphorylase]] | [[Category: Phosphorylase]] | ||
Revision as of 11:07, 30 June 2013
Glycogen Phosphorylase b in complex with GlcIUGlycogen Phosphorylase b in complex with GlcIU
Template:ABSTRACT PUBMED 22267166
FunctionFunction
[PYGM_RABIT] Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
About this StructureAbout this Structure
3t3h is a 1 chain structure with sequence from Oryctolagus cuniculus. Full crystallographic information is available from OCA.
ReferenceReference
- ↑ Kantsadi AL, Hayes JM, Manta S, Skamnaki VT, Kiritsis C, Psarra AM, Koutsogiannis Z, Dimopoulou A, Theofanous S, Nikoleousakos N, Zoumpoulakis P, Kontou M, Papadopoulos G, Zographos SE, Komiotis D, Leonidas DD. The sigma-Hole Phenomenon of Halogen Atoms Forms the Structural Basis of the Strong Inhibitory Potency of C5 Halogen Substituted Glucopyranosyl Nucleosides towards Glycogen Phosphorylase b. ChemMedChem. 2012 Jan 20. doi: 10.1002/cmdc.201100533. PMID:22267166 doi:10.1002/cmdc.201100533