2c4l: Difference between revisions

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[[Image:2c4l.png|left|200px]]
==STRUCTURE OF NEURAMINIDASE SUBTYPE N9 COMPLEXED WITH 30 MM SIALIC ACID (NANA, NEU5AC), CRYSTAL SOAKED FOR 24 HOURS AT 291 K AND FINALLY BACKSOAKED FOR 30 MIN IN A CRYOPROTECTANT SOLUTION WHICH DID NOT CONTAIN NEU5AC==
 
<StructureSection load='2c4l' size='340' side='right' caption='[[2c4l]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
{{STRUCTURE_2c4l|  PDB=2c4l  |  SCENE=  }}
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2c4l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C4L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C4L FirstGlance]. <br>
===STRUCTURE OF NEURAMINIDASE SUBTYPE N9 COMPLEXED WITH 30 MM SIALIC ACID (NANA, NEU5AC), CRYSTAL SOAKED FOR 24 HOURS AT 291 K AND FINALLY BACKSOAKED FOR 30 MIN IN A CRYOPROTECTANT SOLUTION WHICH DID NOT CONTAIN NEU5AC===
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SIA:O-SIALIC+ACID'>SIA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene><br>
 
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a14|1a14]], [[1bji|1bji]], [[1f8b|1f8b]], [[1f8c|1f8c]], [[1f8d|1f8d]], [[1f8e|1f8e]], [[1iny|1iny]], [[1l7f|1l7f]], [[1l7g|1l7g]], [[1l7h|1l7h]], [[1mwe|1mwe]], [[1nca|1nca]], [[1ncb|1ncb]], [[1ncc|1ncc]], [[1nmc|1nmc]], [[1nna|1nna]], [[1nnb|1nnb]], [[1nnc|1nnc]], [[1xoe|1xoe]], [[1xog|1xog]], [[2c4a|2c4a]], [[2qwa|2qwa]], [[2qwb|2qwb]], [[2qwc|2qwc]], [[2qwd|2qwd]], [[2qwe|2qwe]], [[2qwf|2qwf]], [[2qwg|2qwg]], [[2qwh|2qwh]], [[2qwi|2qwi]], [[2qwj|2qwj]], [[2qwk|2qwk]], [[3nn9|3nn9]], [[4nn9|4nn9]], [[5nn9|5nn9]], [[6nn9|6nn9]], [[7nn9|7nn9]]</td></tr>
 
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] </span></td></tr>
==About this Structure==
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c4l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c4l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c4l RCSB], [http://www.ebi.ac.uk/pdbsum/2c4l PDBsum]</span></td></tr>
[[2c4l]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C4L OCA].  
<table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c4/2c4l_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Neuraminidase|Neuraminidase]]
*[[Neuraminidase|Neuraminidase]]
__TOC__
</StructureSection>
[[Category: Exo-alpha-sialidase]]
[[Category: Exo-alpha-sialidase]]
[[Category: Influenza a virus]]
[[Category: Influenza a virus]]

Revision as of 06:27, 29 September 2014

STRUCTURE OF NEURAMINIDASE SUBTYPE N9 COMPLEXED WITH 30 MM SIALIC ACID (NANA, NEU5AC), CRYSTAL SOAKED FOR 24 HOURS AT 291 K AND FINALLY BACKSOAKED FOR 30 MIN IN A CRYOPROTECTANT SOLUTION WHICH DID NOT CONTAIN NEU5ACSTRUCTURE OF NEURAMINIDASE SUBTYPE N9 COMPLEXED WITH 30 MM SIALIC ACID (NANA, NEU5AC), CRYSTAL SOAKED FOR 24 HOURS AT 291 K AND FINALLY BACKSOAKED FOR 30 MIN IN A CRYOPROTECTANT SOLUTION WHICH DID NOT CONTAIN NEU5AC

Structural highlights

2c4l is a 1 chain structure with sequence from Influenza a virus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , ,
Related:1a14, 1bji, 1f8b, 1f8c, 1f8d, 1f8e, 1iny, 1l7f, 1l7g, 1l7h, 1mwe, 1nca, 1ncb, 1ncc, 1nmc, 1nna, 1nnb, 1nnc, 1xoe, 1xog, 2c4a, 2qwa, 2qwb, 2qwc, 2qwd, 2qwe, 2qwf, 2qwg, 2qwh, 2qwi, 2qwj, 2qwk, 3nn9, 4nn9, 5nn9, 6nn9, 7nn9
Activity:Exo-alpha-sialidase, with EC number 3.2.1.18
Resources:FirstGlance, OCA, RCSB, PDBsum

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2c4l, resolution 2.15Å

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