3pka: Difference between revisions
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{{STRUCTURE_3pka| PDB=3pka | SCENE= }} | {{STRUCTURE_3pka| PDB=3pka | SCENE= }} | ||
===M. tuberculosis MetAP with bengamide analog Y02, in Mn form=== | ===M. tuberculosis MetAP with bengamide analog Y02, in Mn form=== | ||
{{ABSTRACT_PUBMED_21465667}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/AMPM2_MYCTU AMPM2_MYCTU]] Removes the N-terminal methionine from nascent proteins, when the penultimate amino acid is alanine or proline, but enzyme activity is remarkably low when the second residue is phenylalanine or leucine. With glycine at the second position, Map is more active with a tetrapeptide than with a tripeptide.<ref>PMID:19688379</ref> <ref>PMID:20038112</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3pka]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PKA OCA]. | [[3pka]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PKA OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:021465667</ref><references group="xtra"/> | <ref group="xtra">PMID:021465667</ref><references group="xtra"/><references/> | ||
[[Category: Methionyl aminopeptidase]] | [[Category: Methionyl aminopeptidase]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||