3eo1: Difference between revisions

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

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-[[Image:3eo1.png|left|200px]]
 {{STRUCTURE_3eo1|  PDB=3eo1  |  SCENE=  }}
+===Structure of the Fab Fragment of GC-1008 in Complex with Transforming Growth Factor-Beta 3===
+{{ABSTRACT_PUBMED_19073914}}
-===Structure of the Fab Fragment of GC-1008 in Complex with Transforming Growth Factor-Beta 3===
+==Disease==
+[[http://www.uniprot.org/uniprot/TGFB3_HUMAN TGFB3_HUMAN]] Defects in TGFB3 are a cause of familial arrhythmogenic right ventricular dysplasia type 1 (ARVD1) [MIM:[http://omim.org/entry/107970 107970]]; also known as arrhythmogenic right ventricular cardiomyopathy 1 (ARVC1). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall.<ref>PMID:15639475</ref>
-{{ABSTRACT_PUBMED_19073914}}
+==Function==
+[[http://www.uniprot.org/uniprot/TGFB3_HUMAN TGFB3_HUMAN]] Involved in embryogenesis and cell differentiation.
 ==About this Structure==
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 ==Reference==
-<ref group="xtra">PMID:019073914</ref><references group="xtra"/>
+<ref group="xtra">PMID:019073914</ref><references group="xtra"/><references/>
 [[Category: Homo sapiens]]
 [[Category: Mus musculus]]