1lbc: Difference between revisions

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[[Image:1lbc.gif|left|200px]]<br /><applet load="1lbc" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1lbc.gif|left|200px]]
caption="1lbc, resolution 1.8&Aring;" />
 
'''Crystal structure of GluR2 ligand binding core (S1S2J-N775S) in complex with cyclothiazide (CTZ) as well as glutamate at 1.8 A resolution'''<br />
{{Structure
|PDB= 1lbc |SIZE=350|CAPTION= <scene name='initialview01'>1lbc</scene>, resolution 1.8&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene> and <scene name='pdbligand=CYZ:CYCLOTHIAZIDE'>CYZ</scene>
|ACTIVITY=
|GENE= GluR-2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])
}}
 
'''Crystal structure of GluR2 ligand binding core (S1S2J-N775S) in complex with cyclothiazide (CTZ) as well as glutamate at 1.8 A resolution'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1LBC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=GLU:'>GLU</scene> and <scene name='pdbligand=CYZ:'>CYZ</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBC OCA].  
1LBC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBC OCA].  


==Reference==
==Reference==
Mechanism of glutamate receptor desensitization., Sun Y, Olson R, Horning M, Armstrong N, Mayer M, Gouaux E, Nature. 2002 May 16;417(6886):245-53. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12015593 12015593]
Mechanism of glutamate receptor desensitization., Sun Y, Olson R, Horning M, Armstrong N, Mayer M, Gouaux E, Nature. 2002 May 16;417(6886):245-53. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12015593 12015593]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: glur2]]
[[Category: glur2]]
[[Category: ligand binding core]]
[[Category: ligand binding core]]
[[Category: n775s]]
[[Category: n775]]
[[Category: point mutation]]
[[Category: point mutation]]
[[Category: s1s2]]
[[Category: s1s2]]


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